Answer: A plenum is an air-return area in a HVAC (Heating Ventilation Air Conditioning) system. A "plenum cable" is a cable rated for use in a plenum area and will be labeled as such.
Please note, plenum is not a type of cable coating or insulation.
Answer: If you are running the cable through or behind walls, through a dropped ceiling or raised floor, you should use cables which are either labeled "in-wall" or "UL type CL2".